Difference between revisions of "CotC"
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''cotC'' (according to [http://dbtbs.hgc.jp/COG/prom/cotC.html DBTBS]) |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigK]] {{PubMed|1518043}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]], [[SpoIIID]]) {{PubMed|1518043,10788508}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[GerE]]: transcription activation {{PubMed|1518043}} | ||
| + | ** [[SpoIIID]]: transcription repression {{PubMed|10788508}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 118: | Line 121: | ||
=References= | =References= | ||
| − | <pubmed>,1518043,2821284,12031481,1691789,18065538 </pubmed> | + | <pubmed>,1518043,2821284,12031481,1691789,18065538 10788508 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:03, 18 October 2009
- Description: spore coat protein (outer)
| Gene name | cotC |
| Synonyms | |
| Essential | no |
| Product | spore coat protein (outer) |
| Function | resistance of the spore |
| MW, pI | 14 kDa, 9.558 |
| Gene length, protein length | 354 bp, 118 aa |
| Immediate neighbours | yncM, tatAC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU17700
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P07790
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: cotC (according to DBTBS)
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Rachele Isticato, Assunta Pelosi, Rita Zilhão, Loredana Baccigalupi, Adriano O Henriques, Maurilio De Felice, Ezio Ricca
CotC-CotU heterodimerization during assembly of the Bacillus subtilis spore coat.
J Bacteriol: 2008, 190(4);1267-75
[PubMed:18065538]
[WorldCat.org]
[DOI]
(I p)
Dinene L Crater, Kathryn H Wade, Orna Resnekov, H Travis Ichikawa, Lee Kroos, James A Brannigan, Charles P Moran
A mutation in GerE that affects cotC promoter activation in Bacillus subtilis.
Biochim Biophys Acta: 2002, 1576(1-2);30-8
[PubMed:12031481]
[WorldCat.org]
[DOI]
(P p)
H Ichikawa, L Kroos
Combined action of two transcription factors regulates genes encoding spore coat proteins of Bacillus subtilis.
J Biol Chem: 2000, 275(18);13849-55
[PubMed:10788508]
[WorldCat.org]
[DOI]
(P p)
L Zheng, R Halberg, S Roels, H Ichikawa, L Kroos, R Losick
Sporulation regulatory protein GerE from Bacillus subtilis binds to and can activate or repress transcription from promoters for mother-cell-specific genes.
J Mol Biol: 1992, 226(4);1037-50
[PubMed:1518043]
[WorldCat.org]
[DOI]
(P p)
L B Zheng, R Losick
Cascade regulation of spore coat gene expression in Bacillus subtilis.
J Mol Biol: 1990, 212(4);645-60
[PubMed:1691789]
[WorldCat.org]
[DOI]
(P p)
W Donovan, L B Zheng, K Sandman, R Losick
Genes encoding spore coat polypeptides from Bacillus subtilis.
J Mol Biol: 1987, 196(1);1-10
[PubMed:2821284]
[WorldCat.org]
[DOI]
(P p)
