Difference between revisions of "LipC"
| Line 1: | Line 1: | ||
| − | * '''Description:''' | + | * '''Description:''' phospholipase implicated in spore germination <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || spore coat phospholipase B |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || spore germination | |style="background:#ABCDEF;" align="center"|'''Function''' || spore germination | ||
| Line 38: | Line 38: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | + | defective in L-alanine-stimulated germination {{PubMed|20057119}} | |
=== Database entries === | === Database entries === | ||
| Line 52: | Line 52: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' cleaves the fatty acids at the sn-1 and sn-2 positions of phospholipids {{PubMed|20057119}} |
* '''Protein family:''' 'GDSL' lipolytic enzyme family (according to Swiss-Prot) | * '''Protein family:''' 'GDSL' lipolytic enzyme family (according to Swiss-Prot) | ||
| Line 72: | Line 72: | ||
* '''Interactions:''' | * '''Interactions:''' | ||
| − | * '''Localization:''' spore | + | * '''Localization:''' spore coat {{PubMed|20057119}}, mother cell [http://www.ncbi.nlm.nih.gov/sites/entrez/17220230 PubMed] |
=== Database entries === | === Database entries === | ||
| Line 122: | Line 122: | ||
=References= | =References= | ||
| − | <pubmed> 17220230 9334321</pubmed> | + | <pubmed> 17220230 9334321 20057119 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:38, 9 January 2010
- Description: phospholipase implicated in spore germination
| Gene name | lipC |
| Synonyms | ycsK |
| Essential | no |
| Product | spore coat phospholipase B |
| Function | spore germination |
| MW, pI | 23 kDa, 5.839 |
| Gene length, protein length | 639 bp, 213 aa |
| Immediate neighbours | kipR, yczI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU04110
Phenotypes of a mutant
defective in L-alanine-stimulated germination PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: cleaves the fatty acids at the sn-1 and sn-2 positions of phospholipids PubMed
- Protein family: 'GDSL' lipolytic enzyme family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
Database entries
- Structure:
- UniProt: P42969
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Atsushi Masayama, Shiro Kato, Takuya Terashima, Anne Mølgaard, Hisashi Hemmi, Tohru Yoshimura, Ryuichi Moriyama
Bacillus subtilis spore coat protein LipC is a phospholipase B.
Biosci Biotechnol Biochem: 2010, 74(1);24-30
[PubMed:20057119]
[WorldCat.org]
[DOI]
(I p)
Atsushi Masayama, Ritsuko Kuwana, Hiromu Takamatsu, Hisashi Hemmi, Tohru Yoshimura, Kazuhito Watabe, Ryuichi Moriyama
A novel lipolytic enzyme, YcsK (LipC), located in the spore coat of Bacillus subtilis, is involved in spore germination.
J Bacteriol: 2007, 189(6);2369-75
[PubMed:17220230]
[WorldCat.org]
[DOI]
(P p)
L Wang, R Grau, M Perego, J A Hoch
A novel histidine kinase inhibitor regulating development in Bacillus subtilis.
Genes Dev: 1997, 11(19);2569-79
[PubMed:9334321]
[WorldCat.org]
[DOI]
(P p)
