CsgA

• Description: required for the ability of the germinating spore to resume vegetative growth
  
  

Gene name	csgA
Synonyms
Essential	no
Product	unknown
Function	spore germination
MW, pI	9 kDa, 4.694
Gene length, protein length	246 bp, 82 aa
Immediate neighbours	ybxG, ybxH
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU02070

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P54379

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: csgA-ybxH

• Sigma factor: SigG PubMed

• Regulation:
  • expressed during sporulation in the forespore (SpoVT) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

M Shcheptov, G Chyu, I Bagyan, S Cutting
Characterization of csgA, a new member of the forespore-expressed sigmaG-regulon from Bacillus subtilis.
Gene: 1997, 184(1);133-40
[PubMed:9016963] [WorldCat.org] [DOI] (P p)