Difference between revisions of "CotT"

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* '''Localization:''' spore wall (according to Swiss-Prot)
 
* '''Localization:''' spore wall (according to Swiss-Prot)
 
+
''Italic text''
 
=== Database entries ===
 
=== Database entries ===
  
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''cotT'' {{PubMed|2546006}}
  
* '''[[Sigma factor]]:''' [[SigK]] {{PubMed|15699190}}
+
* '''[[Sigma factor]]:''' [[SigK]] {{PubMed|2546006,15699190,15383836}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** expressed late during sporulation in the mother cell ([[SigK]]) {{PubMed|2546006,15699190,15383836}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[SpoIIID]]: transcription activation {{PubMed|15383836}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
  
<pubmed>10714992,1917883,, </pubmed>
+
<pubmed>10714992,1917883,2546006,15699190, 15383836 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:05, 29 September 2009

  • Description: spore coat protein (inner)

Gene name cotT
Synonyms
Essential no
Product spore coat protein (inner)
Function resistance of the spore
MW, pI 12 kDa, 9.466
Gene length, protein length 321 bp, 107 aa
Immediate neighbours ctaO, yjeA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CotT context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU12090

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: spore wall (according to Swiss-Prot)

Italic text

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Arthur Aronson, Purdue University, West Lafayette, USA homepage

Your additional remarks

References

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836] [WorldCat.org] [DOI] (I p)

H Takamatsu, T Kodama, A Imamura, K Asai, K Kobayashi, T Nakayama, N Ogasawara, K Watabe
The Bacillus subtilis yabG gene is transcribed by SigK RNA polymerase during sporulation, and yabG mutant spores have altered coat protein composition.
J Bacteriol: 2000, 182(7);1883-8
[PubMed:10714992] [WorldCat.org] [DOI] (P p)

N Bourne, P C FitzJames, A I Aronson
Structural and germination defects of Bacillus subtilis spores with altered contents of a spore coat protein.
J Bacteriol: 1991, 173(20);6618-25
[PubMed:1917883] [WorldCat.org] [DOI] (P p)

A I Aronson, H Y Song, N Bourne
Gene structure and precursor processing of a novel Bacillus subtilis spore coat protein.
Mol Microbiol: 1989, 3(3);437-44
[PubMed:2546006] [WorldCat.org] [DOI] (P p)