Difference between revisions of "ManA"

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=Expression and regulation=
 
=Expression and regulation=
 +
* '''Operon:''' ''[[manP]]-[[manA]]-[[yjdF]]'' {{PubMed|20139185}}
  
* '''Operon:'''
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|20139185}}
 
 
* '''[[Sigma factor]]:'''  
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** induced by mannose ([[ManR]]) {{PubMed|20139185}}
 +
** repressed by glucose ([[ManR]]) {{PubMed|20139185}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[ManR]]: transcription activation in the presence of mannose and absence of glucose {{PubMed|20139185}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
  
<pubmed>10960106,,10627040, </pubmed>
+
<pubmed>10960106, 20139185,10627040, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 12:28, 9 February 2010

  • Description: mannose-6-phosphate isomerase

Gene name manA
Synonyms yjdE
Essential no
Product mannose-6-phosphate isomerase
Function mannose utilization
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 35 kDa, 5.279
Gene length, protein length 945 bp, 315 aa
Immediate neighbours manP, yjdF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ManA context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU12020

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
    • ManR: transcription activation in the presence of mannose and absence of glucose PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References