Difference between revisions of "BioA"
(→Database entries) |
|||
| Line 76: | Line 76: | ||
=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3DRD 3DRD] |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P53555 P53555] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P53555 P53555] | ||
Revision as of 19:44, 13 October 2009
- Description: lysine-8-amino-7-oxononanoate aminotransferase
| Gene name | bioA |
| Synonyms | |
| Essential | no |
| Product | lysine-8-amino-7-oxononanoate aminotransferase |
| Function | biosynthesis of biotin |
| MW, pI | 49 kDa, 5.32 |
| Gene length, protein length | 1344 bp, 448 aa |
| Immediate neighbours | bioF, bioW |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU30230
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: class-III pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 3DRD
- UniProt: P53555
- KEGG entry: [3]
- E.C. number: 2.6.1.62
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Scott W Van Arsdell, John B Perkins, R Rogers Yocum, Linda Luan, C Linda Howitt, Nilu Prasad Chatterjee, Janice G Pero
Removing a bottleneck in the Bacillus subtilis biotin pathway: bioA utilizes lysine rather than S-adenosylmethionine as the amino donor in the KAPA-to-DAPA reaction.
Biotechnol Bioeng: 2005, 91(1);75-83
[PubMed:15880481]
[WorldCat.org]
[DOI]
(P p)
J B Perkins, S Bower, C L Howitt, R R Yocum, J Pero
Identification and characterization of transcripts from the biotin biosynthetic operon of Bacillus subtilis.
J Bacteriol: 1996, 178(21);6361-5
[PubMed:8892842]
[WorldCat.org]
[DOI]
(P p)
S Bower, J B Perkins, R R Yocum, C L Howitt, P Rahaim, J Pero
Cloning, sequencing, and characterization of the Bacillus subtilis biotin biosynthetic operon.
J Bacteriol: 1996, 178(14);4122-30
[PubMed:8763940]
[WorldCat.org]
[DOI]
(P p)
