Difference between revisions of "AbfA"
(→Expression and regulation) |
|||
| Line 91: | Line 91: | ||
=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''[[araA]]-[[araB]]-[[araD]]-[[araL]]-[[araM]]-[[araN]]-[[araP]]-[[araQ]]-[[abfA]]'' {{PubMed|9084180}} | ||
| − | * ''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9084180}} |
| − | * '''[[ | + | * '''Regulation:''' |
| + | ** repressed by glucose ([[CcpA]]) {{PubMed|12949161}} | ||
| + | ** induced by arabinose ([[AraR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed] | ||
| − | * ''' | + | * '''Regulatory mechanism:''' |
| − | ** | + | ** [[CcpA]]: transcription repression {{PubMed|12949161}} |
| − | |||
| − | |||
** [[AraR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed] | ** [[AraR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed] | ||
Revision as of 21:58, 15 December 2009
- Description: alpha-L-arabinofuranosidase
| Gene name | abfA |
| Synonyms | |
| Essential | no |
| Product | alpha-L-arabinofuranosidase |
| Function | arabinan degradation |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 56 kDa, 5.344 |
| Gene length, protein length | 1500 bp, 500 aa |
| Immediate neighbours | cstA, araQ |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU28720
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides (according to Swiss-Prot)
- Protein family: glycosyl hydrolase 51 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure: 1QW8 (complex with Ara-alpha-Xyl, Geobacillus stearothermophilus), 1PZ3 (Geobacillus stearothermophilus)
- UniProt: P94531
- KEGG entry: [3]
- E.C. number: 3.2.1.55
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
