Difference between revisions of "DacC"
| Line 18: | Line 18: | ||
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1473 bp, 491 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1473 bp, 491 aa | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ppsA]]'', ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ppsA]]'', ''[[galM]]'' |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB13718]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB13718]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | ||
| Line 52: | Line 52: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' cleavage ofD-Ala-D-Ala interpeptide bridges in peptidoglycan {{PubMed|19758330}} |
| − | * '''Protein family:''' | + | * '''Protein family:''' |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[galM]]-[[dacC]]'' {{PubMed|9733705}} |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigH]] {{PubMed|9733705}}, [[SigB]] {{PubMed|10482513}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| Line 117: | Line 117: | ||
=References= | =References= | ||
| − | + | <pubmed> 9733705 10482513 19758330 14731276,,9864321, </pubmed> | |
| − | <pubmed>9733705 | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:48, 18 September 2009
- Description: penicillin-binding protein 4A, D-alanyl-D-alanine carboxypeptidase
| Gene name | dacC |
| Synonyms | pbp |
| Essential | no |
| Product | penicillin-binding protein 4A, D-alanyl-D-alanine carboxypeptidase |
| Function | carboxypeptidase |
| MW, pI | 52 kDa, 5.413 |
| Gene length, protein length | 1473 bp, 491 aa |
| Immediate neighbours | ppsA, galM |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU18350
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: cleavage ofD-Ala-D-Ala interpeptide bridges in peptidoglycan PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- UniProt: P39844
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Colette Duez, Astrid Zervosen, Nathalie Teller, Rémy Melkonian, Emmanuel Banzubazé, Fabrice Bouillenne, André Luxen, Jean-Marie Frère
Characterization of the proteins encoded by the Bacillus subtilis yoxA-dacC operon.
FEMS Microbiol Lett: 2009, 300(1);42-7
[PubMed:19758330]
[WorldCat.org]
[DOI]
(I p)
Dirk-Jan Scheffers, Laura J F Jones, Jeffery Errington
Several distinct localization patterns for penicillin-binding proteins in Bacillus subtilis.
Mol Microbiol: 2004, 51(3);749-64
[PubMed:14731276]
[WorldCat.org]
[DOI]
(P p)
A Petersohn, J Bernhardt, U Gerth, D Höper, T Koburger, U Völker, M Hecker
Identification of sigma(B)-dependent genes in Bacillus subtilis using a promoter consensus-directed search and oligonucleotide hybridization.
J Bacteriol: 1999, 181(18);5718-24
[PubMed:10482513]
[WorldCat.org]
[DOI]
(P p)
D L Popham, M E Gilmore, P Setlow
Roles of low-molecular-weight penicillin-binding proteins in Bacillus subtilis spore peptidoglycan synthesis and spore properties.
J Bacteriol: 1999, 181(1);126-32
[PubMed:9864321]
[WorldCat.org]
[DOI]
(P p)
L B Pedersen, T Murray, D L Popham, P Setlow
Characterization of dacC, which encodes a new low-molecular-weight penicillin-binding protein in Bacillus subtilis.
J Bacteriol: 1998, 180(18);4967-73
[PubMed:9733705]
[WorldCat.org]
[DOI]
(P p)
