Difference between revisions of "BacC"

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|style="background:#ABCDEF;" align="center"| '''Product''' || bacilysin biosynthesis oxidoreductase
 
|style="background:#ABCDEF;" align="center"| '''Product''' || bacilysin biosynthesis oxidoreductase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || bacilysin production
+
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of the antibiotic bacilysin
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 4.959   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 4.959   
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[bacA]]-[[bacB]]-[[bacC]]-[[bacD]]-[[bacE]]-[[bacF]]'' {{PubMed|12372825}}
  
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[CodY]]: transcription repression {{PubMed|12372825}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
  
<pubmed>15609023,, </pubmed>
+
<pubmed>15609023 12372825</pubmed>

Revision as of 21:29, 9 July 2009

  • Description: bacilysin biosynthesis oxidoreductase

Gene name bacC
Synonyms ywfD, ipa-82d
Essential no
Product bacilysin biosynthesis oxidoreductase
Function biosynthesis of the antibiotic bacilysin
MW, pI 27 kDa, 4.959
Gene length, protein length 765 bp, 255 aa
Immediate neighbours bacD, bacB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwfD context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU37720

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Gerhard Steinborn, Mohammad-Reza Hajirezaei, Jürgen Hofemeister
bac genes for recombinant bacilysin and anticapsin production in Bacillus host strains.
Arch Microbiol: 2005, 183(2);71-9
[PubMed:15609023] [WorldCat.org] [DOI] (P p)

Takashi Inaoka, Kosaku Takahashi, Mayumi Ohnishi-Kameyama, Mitsuru Yoshida, Kozo Ochi
Guanine nucleotides guanosine 5'-diphosphate 3'-diphosphate and GTP co-operatively regulate the production of an antibiotic bacilysin in Bacillus subtilis.
J Biol Chem: 2003, 278(4);2169-76
[PubMed:12372825] [WorldCat.org] [DOI] (P p)