Difference between revisions of "Ldh"
| Line 82: | Line 82: | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1LDN 1LDN] (+) and fructose-1.6-bisphosphate, Geobacillus stearothermophilus), [http://www.rcsb.org/pdb/explore.do?structureId=2LDB 2LDB] (Geobacillus stearothermophilus) | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1LDN 1LDN] (+) and fructose-1.6-bisphosphate, Geobacillus stearothermophilus), [http://www.rcsb.org/pdb/explore.do?structureId=2LDB 2LDB] (Geobacillus stearothermophilus) | ||
| − | * ''' | + | * '''UniProt:''' [http://www.uniprot.org/uniprot/P13714 P13714] |
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU03050] | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU03050] | ||
Revision as of 10:32, 20 July 2009
- Description: L-lactate dehydrogenase
| Gene name | ldh |
| Synonyms | lctE |
| Essential | no |
| Product | L-lactate dehydrogenase |
| Function | overflow metabolism, fermentation |
| Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
| MW, pI | 34 kDa, 5.394 |
| Gene length, protein length | 963 bp, 321 aa |
| Immediate neighbours | amyE, lctP |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU03050
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (S)-lactate + NAD+ = pyruvate + NADH (according to Swiss-Prot)
- Protein family: LDH family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation on Tyr-224 PubMed
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 1LDN (+) and fructose-1.6-bisphosphate, Geobacillus stearothermophilus), 2LDB (Geobacillus stearothermophilus)
- UniProt: P13714
- KEGG entry: [3]
- E.C. number: 1.1.1.27
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
