Difference between revisions of "RsgI"
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigI]] activity | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigI]] activity | ||
+ | |- | ||
+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13460 rsgI] | ||
+ | |- | ||
+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=RsgI RsgI] | ||
+ | |- | ||
+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=rsgI rsgI]''' | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 4.517 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 4.517 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sigI]]'', ''[[sspD]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sigI]]'', ''[[sspD]]'' | ||
|- | |- | ||
− | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU13460 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU13460 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU13460 DNA_with_flanks] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:ykrI_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ykrI_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
+ | |- | ||
+ | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rsgI_1412644_1413789_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:rsgI_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13460]] | ||
|- | |- | ||
|} | |} | ||
__TOC__ | __TOC__ | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
− | <br/><br/> | + | |
+ | <br/><br/><br/><br/><br/><br/> | ||
+ | |||
+ | = [[Categories]] containing this gene/protein = | ||
+ | {{SubtiWiki category|[[sigma factors and their control]]}}, | ||
+ | {{SubtiWiki category|[[heat shock proteins]]}}, | ||
+ | {{SubtiWiki category|[[membrane proteins]]}} | ||
+ | |||
+ | = This gene is a member of the following [[regulons]] = | ||
+ | {{SubtiWiki regulon|[[SigI regulon]]}} | ||
=The gene= | =The gene= | ||
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=== Basic information === | === Basic information === | ||
− | * ''' | + | * '''Locus tag:''' BSU13460 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
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=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU13460&redirect=T BSU13460] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/sigI-rsgI.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/sigI-rsgI.html] | ||
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=== Additional information=== | === Additional information=== | ||
+ | |||
+ | |||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
− | * '''Interactions:''' [[RsgI]]-[[SigI]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17185538 PubMed] | + | * '''[[SubtInteract|Interactions]]:''' |
+ | ** [[RsgI]]-[[SigI]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17185538 PubMed] | ||
− | * '''Localization:''' membrane [http://www.ncbi.nlm.nih.gov/sites/entrez/17185538 PubMed] | + | * '''[[Localization]]:''' |
+ | ** membrane [http://www.ncbi.nlm.nih.gov/sites/entrez/17185538 PubMed] | ||
=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU13460&redirect=T BSU13460] | ||
* '''Structure:''' | * '''Structure:''' | ||
− | * ''' | + | * '''UniProt:''' [http://www.uniprot.org/uniprot/O31655 O31655] |
− | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU13460] |
* '''E.C. number:''' | * '''E.C. number:''' | ||
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* '''Operon:''' ''[[sigI]]-[[rsgI]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/17185538 PubMed] | * '''Operon:''' ''[[sigI]]-[[rsgI]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/17185538 PubMed] | ||
+ | |||
+ | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rsgI_1412644_1413789_1 rsgI] {{PubMed|22383849}} | ||
* '''Sigma factor:''' [[SigI]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17185538 PubMed] | * '''Sigma factor:''' [[SigI]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17185538 PubMed] | ||
− | * '''Regulation:''' induced | + | * '''Regulation:''' |
+ | ** induced at high temperature ([[SigI]], [[WalR]]) {{PubMed|23199363,17185538}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
+ | ** [[WalR]]: transcription activation {{PubMed|23199363}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
− | + | <pubmed>17185538,23199363,17185538 19114499, </pubmed> | |
− | + | ||
− | + | [[Category:Protein-coding genes]] |
Latest revision as of 13:32, 2 April 2014
- Description: regulator of SigI activity
Gene name | rsgI |
Synonyms | ykrI |
Essential | no |
Product | anti-sigma factor |
Function | control of SigI activity |
Gene expression levels in SubtiExpress: rsgI | |
Interactions involving this protein in SubtInteract: RsgI | |
Metabolic function and regulation of this protein in SubtiPathways: rsgI | |
MW, pI | 43 kDa, 4.517 |
Gene length, protein length | 1143 bp, 381 aa |
Immediate neighbours | sigI, sspD |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
sigma factors and their control, heat shock proteins, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU13460
Phenotypes of a mutant
suppresses the growth defect of a mbl mutation PubMed
Database entries
- BsubCyc: BSU13460
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- membrane PubMed
Database entries
- BsubCyc: BSU13460
- Structure:
- UniProt: O31655
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Letal I Salzberg, Leagh Powell, Karsten Hokamp, Eric Botella, David Noone, Kevin M Devine
The WalRK (YycFG) and σ(I) RsgI regulators cooperate to control CwlO and LytE expression in exponentially growing and stressed Bacillus subtilis cells.
Mol Microbiol: 2013, 87(1);180-95
[PubMed:23199363]
[WorldCat.org]
[DOI]
(I p)
Kathrin Schirner, Jeff Errington
The cell wall regulator {sigma}I specifically suppresses the lethal phenotype of mbl mutants in Bacillus subtilis.
J Bacteriol: 2009, 191(5);1404-13
[PubMed:19114499]
[WorldCat.org]
[DOI]
(I p)
Kei Asai, Takafumi Ootsuji, Kazue Obata, Takashi Matsumoto, Yasutaro Fujita, Yoshito Sadaie
Regulatory role of RsgI in sigI expression in Bacillus subtilis.
Microbiology (Reading): 2007, 153(Pt 1);92-101
[PubMed:17185538]
[WorldCat.org]
[DOI]
(P p)