Difference between revisions of "Replisome"

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(In vitro reconstitution of the replisome)
 
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[[PolC]]-[[HolA]]-[[HolB]]-[[DnaX]]-[[DnaN]]-[[DnaG]]-[[DnaC]]-[[DnaI]]-[[DnaD]]-[[SsbA]]-[[DnaE]]-[[PriA]]-[[DnaB]] {{PubMed|20122408}}
 
[[PolC]]-[[HolA]]-[[HolB]]-[[DnaX]]-[[DnaN]]-[[DnaG]]-[[DnaC]]-[[DnaI]]-[[DnaD]]-[[SsbA]]-[[DnaE]]-[[PriA]]-[[DnaB]] {{PubMed|20122408}}
  
==Back to [[protein-protein interactions]]==
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[[RecA]] colocalizes to the [[replisome]] in response to endogenous and exogenous DNA damage and in response to damage-independent fork arrest (formation of DNA repair centers), repair center formation depends on [[RecO]] and [[RecR]], and is facilitated by [[RecF]] and [[SsbA]] {{PubMed|24891441}}
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==Related pages==
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* [[DNA replication]]
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==Back to [[Protein-protein interactions]]==
  
 
==''In vitro'' reconstitution of the replisome==
 
==''In vitro'' reconstitution of the replisome==
<pubmed> 20122408 </pubmed>
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<pubmed> 20122408 35635709 </pubmed>
  
 
==Reviews==
 
==Reviews==
<pubmed> 16036556 </pubmed>
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<pubmed>26097470 16036556 21675919,29856930 </pubmed>
  
 
==Other important publications==
 
==Other important publications==
<pubmed> 21350489 </pubmed>
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<pubmed> 21350489 21419346</pubmed>
 
 
==Related pages==
 
* [[DNA replication]]
 
 
 
==Back to [[Protein-protein interactions]]==
 

Latest revision as of 10:54, 20 June 2022

The replisome is a protein complex that is required and sufficient for replication of both leading and lagging strands.

PolC-HolA-HolB-DnaX-DnaN-DnaG-DnaC-DnaI-DnaD-SsbA-DnaE-PriA-DnaB PubMed

RecA colocalizes to the replisome in response to endogenous and exogenous DNA damage and in response to damage-independent fork arrest (formation of DNA repair centers), repair center formation depends on RecO and RecR, and is facilitated by RecF and SsbA PubMed

Related pages

Back to Protein-protein interactions

In vitro reconstitution of the replisome


Reviews


Other important publications