Difference between revisions of "Transcription factors of the LacI family"

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===These [[transcription factors and their control|transcription factors]] resemble the ''E. coli'' Lac repressor (LacI). They are involved in the control of sugar catabolic operons in response to the availability of the carbon source. [[CcpA]] is the pleiotropic regulator of carbon catabolite repression.===
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* [[AraR]]
 
* [[CcpA]]
 
* [[CcpA]]
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* [[CcpB]]
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* [[DegA]]
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* [[ExuR]]
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* [[KdgR]]
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* [[LacR]]
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* [[MsmR]]
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* [[NtdR]]
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* [[RbsR]]
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* [[YkvZ]]
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* [[YvdE]]
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==Important publications==
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<pubmed> 21085639 20512969 19818797 19269243 12598694 8543068 1639817 </pubmed>
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= Back to [[Transcription factors and their control]] =
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= Back to [[Protein families]] =

Latest revision as of 17:33, 6 September 2018

These transcription factors resemble the E. coli Lac repressor (LacI). They are involved in the control of sugar catabolic operons in response to the availability of the carbon source. CcpA is the pleiotropic regulator of carbon catabolite repression.

Important publications

Francisco M Camas, Eric J Alm, Juan F Poyatos
Local gene regulation details a recognition code within the LacI transcriptional factor family.
PLoS Comput Biol: 2010, 6(11);e1000989
[PubMed:21085639] [WorldCat.org] [DOI] (I e)

Leslie Milk, Robert Daber, Mitchell Lewis
Functional rules for lac repressor-operator associations and implications for protein-DNA interactions.
Protein Sci: 2010, 19(6);1162-72
[PubMed:20512969] [WorldCat.org] [DOI] (I p)

Sudheer Tungtur, Sarah Meinhardt, Liskin Swint-Kruse
Comparing the functional roles of nonconserved sequence positions in homologous transcription repressors: implications for sequence/function analyses.
J Mol Biol: 2010, 395(4);785-802
[PubMed:19818797] [WorldCat.org] [DOI] (I p)

Liskin Swint-Kruse, Kathleen S Matthews
Allostery in the LacI/GalR family: variations on a theme.
Curr Opin Microbiol: 2009, 12(2);129-37
[PubMed:19269243] [WorldCat.org] [DOI] (I p)

Kaoru Fukami-Kobayashi, Yoshio Tateno, Ken Nishikawa
Parallel evolution of ligand specificity between LacI/GalR family repressors and periplasmic sugar-binding proteins.
Mol Biol Evol: 2003, 20(2);267-77
[PubMed:12598694] [WorldCat.org] [DOI] (P p)

C C Nguyen, M H Saier
Phylogenetic, structural and functional analyses of the LacI-GalR family of bacterial transcription factors.
FEBS Lett: 1995, 377(2);98-102
[PubMed:8543068] [WorldCat.org] [DOI] (P p)

M J Weickert, S Adhya
A family of bacterial regulators homologous to Gal and Lac repressors.
J Biol Chem: 1992, 267(22);15869-74
[PubMed:1639817] [WorldCat.org] (P p)


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