SboA

• Description: subtilosin A
  
  

Gene name	sboA
Synonyms	sbo
Essential	no
Product	subtilosin A
Function	antimicrobial peptide
MW, pI	4 kDa, 4.569
Gene length, protein length	129 bp, 43 aa
Immediate neighbours	ywiB, sboX
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU37350

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: bacteriocin class V family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: secreted (according to Swiss-Prot)

Database entries

• Structure: 1PXQ

• Swiss prot entry: O07623

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sboA-sboX-albA-albB-albC-albD-albE-albF-albG

• Sigma factor: SigA

• Regulation:
  • repressed by Rok PubMed
  • expressed under anaerobic conditions (ResD) PubMed
  • repressed during logrithmic growth (AbrB) PubMed

• Regulatory mechanism:
  • Rok: transcription repression PubMed
  • ResD: transcription activation PubMed
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed