Difference between revisions of "PucA"

From SubtiWiki
Jump to: navigation, search
Line 93: Line 93:
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** repressed in the absence of purine nucleotides (inducer: allantoin) ([[PucR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12029039 PubMed]
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [PucR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12029039 PubMed]
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  

Revision as of 17:05, 11 June 2009

  • Description: xanthine dehydrogenase

Gene name pucA
Synonyms yurF
Essential no
Product xanthine dehydrogenase
Function purine utilization
MW, pI 36 kDa, 6.359
Gene length, protein length 990 bp, 330 aa
Immediate neighbours pucB, pucG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PucA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU32510

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Xanthine + NAD+ + H2O = urate + NADH (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • repressed in the absence of purine nucleotides (inducer: allantoin) (PucR) PubMed
  • Regulatory mechanism:
    • [PucR]]: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed