Difference between revisions of "AraA"

From SubtiWiki
Jump to: navigation, search
Line 35: Line 35:
 
=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU28800
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
Line 80: Line 80:
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P94523 P94523]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P94523 P94523]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU28800 BSU28800]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU28800]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/5.3.1.4 5.3.1.4]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/5.3.1.4 5.3.1.4]

Revision as of 09:13, 3 June 2009

  • Description: L-arabinose isomerase

Gene name araA
Synonyms
Essential no
Product L-arabinose isomerase
Function arabinose utilization
MW, pI 56 kDa, 5.474
Gene length, protein length 1494 bp, 498 aa
Immediate neighbours araB, abnA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AraA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU28800

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-arabinose = L-ribulose (according to Swiss-Prot)
  • Protein family: arabinose isomerase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Inácio JM, Costa C, de Sá-Nogueira I. (2003) Distinct molecular mechanisms involved in carbon catabolite repression of the arabinose regulon in Bacillus subtilis. Microbiology. Sep;149(Pt 9): 2345-55. PubMed
  2. Sa-Nogueira I.M.G., Nogueira T.V., Soares S., de Lencastre H. (1997) The Bacillus subtilis L-arabinose (ara) operon: nucleotide sequence, genetic organization and expression. Microbiology. Mar;143(Pt 3): 957-69. PubMed