Mdr

• Description: multidrug-efflux transporter (puromycin, nerfloxacin, tosufloxacin)
  
  

Gene name	mdr
Synonyms	ycgD, bmr3
Essential	no
Product	multidrug-efflux transporter (puromycin, nerfloxacin, tosufloxacin)
Function	drug resistance
MW, pI	46 kDa, 9.701
Gene length, protein length	1278 bp, 426 aa
Immediate neighbours	lctP, ycgE
Gene sequence (+200bp)	Protein sequence
Caution: The sequence for this gene in SubtiList contains errors
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry:

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation: expression activated by glucose (3.61) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149 PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed