Difference between revisions of "Glutamate metabolism"

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(Proteins involved in glutamate metabolism)
 
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= [http://www.subtiwiki.uni-goettingen.de/wiki/images/b/ba/PhD_position_FM_Commichau.pdf Open Ph.D. position to study glutamate metabolism in ''Bacillus subtilis''] =
 
 
 
 
= Proteins involved in glutamate metabolism =
 
= Proteins involved in glutamate metabolism =
  
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* Ammonium uptake: [[NrgA|AmtB]]
 
* Ammonium uptake: [[NrgA|AmtB]]
 
* Glutamine uptake: [[GlnT]], [[GlnQ]]-([[GlnM]]-[[GlnP]])-[[GlnH]]
 
* Glutamine uptake: [[GlnT]], [[GlnQ]]-([[GlnM]]-[[GlnP]])-[[GlnH]]
* Glutamate uptake: [[GltT]]
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* Glutamate uptake: [[YbeC]], [[GltT]]
  
 
=== Metabolic enzymes===
 
=== Metabolic enzymes===
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= Important publications =
 
= Important publications =
 
==Reviews==
 
==Reviews==
<big>''Gunka K, Commichau FM''  </big> 
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<pubmed>18086213,17982469,16458044,10231480 22625175</pubmed>
<big>'''Control of glutamate homeostasis in ''Bacillus subtilis'':''' </big>
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== Important original publications ==
<big>'''a complex interplay between ammonium assimilation, ''' </big>
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<pubmed>23811508 </pubmed>
<big>'''glutamate biosynthesis and degradation. ''' </big>
 
<big>Mol Microbiol.: 2012, 85(2) 213-224. </big>
 
[http://www.ncbi.nlm.nih.gov/pubmed/22625175 PubMed:22625175]
 
<pubmed>18086213,17982469,16458044,10231480</pubmed>
 

Latest revision as of 10:44, 6 May 2021

Proteins involved in glutamate metabolism

Transport systems

Metabolic enzymes

Regulators

  • Key transcriptional regulators of nitrogen metabolism: GlnR, GltC, TnrA
  • Additional transcriptional regulators: AhrC, RocR, CcpA, Fur
  • Control of ammonium uptake: GlnK

Relevant SubtiWiki pages

Glutamate metabolism in SubtiPathways: Ammonium/ glutamate

Additional websites

Labs studying glutamate metabolism

Important publications

Reviews

Katrin Gunka, Fabian M Commichau
Control of glutamate homeostasis in Bacillus subtilis: a complex interplay between ammonium assimilation, glutamate biosynthesis and degradation.
Mol Microbiol: 2012, 85(2);213-24
[PubMed:22625175] [WorldCat.org] [DOI] (I p)

Fabian M Commichau, Jörg Stülke
Trigger enzymes: bifunctional proteins active in metabolism and in controlling gene expression.
Mol Microbiol: 2008, 67(4);692-702
[PubMed:18086213] [WorldCat.org] [DOI] (P p)

Abraham L Sonenshein
Control of key metabolic intersections in Bacillus subtilis.
Nat Rev Microbiol: 2007, 5(12);917-27
[PubMed:17982469] [WorldCat.org] [DOI] (I p)

Fabian M Commichau, Karl Forchhammer, Jörg Stülke
Regulatory links between carbon and nitrogen metabolism.
Curr Opin Microbiol: 2006, 9(2);167-72
[PubMed:16458044] [WorldCat.org] [DOI] (P p)

S H Fisher
Regulation of nitrogen metabolism in Bacillus subtilis: vive la différence!
Mol Microbiol: 1999, 32(2);223-32
[PubMed:10231480] [WorldCat.org] [DOI] (P p)

Important original publications

Anne Krog, Tonje Marita Bjerkan Heggeset, Trond Erling Ellingsen, Trygve Brautaset
Functional characterization of key enzymes involved in L-glutamate synthesis and degradation in the thermotolerant and methylotrophic bacterium Bacillus methanolicus.
Appl Environ Microbiol: 2013, 79(17);5321-8
[PubMed:23811508] [WorldCat.org] [DOI] (I p)