Difference between revisions of "Glutamate metabolism"

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(Proteins involved in glutamate metabolism)
 
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== Reviews ==
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= Proteins involved in glutamate metabolism =
<pubmed> 18086213 16458044 </pubmed>
 
  
==Regulation of glutamate synthase expression==
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=== Transport systems ===
<pubmed> 14523131 17183217 17608797 20630473 </pubmed>
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* Ammonium uptake: [[NrgA|AmtB]]
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* Glutamine uptake: [[GlnT]], [[GlnQ]]-([[GlnM]]-[[GlnP]])-[[GlnH]]
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* Glutamate uptake: [[YbeC]], [[GltT]]
  
==Regulatory protein-protein interactions in nitrogen regulation==
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=== Metabolic enzymes===
<pubmed> 17001076 17608797 </pubmed>
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* Glutamine synthetase: [[GlnA]]
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* Glutamate synthase: [[GltA]], [[GltB]]
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* Glutamate dehydrogenases: [[GudB]], [[RocG]]
  
== Glutamate homeostasis by  the acquisition of mutations ==
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=== Regulators ===
<pubmed> 18326565 21219666 22178973 </pubmed>
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* Key transcriptional regulators of nitrogen metabolism: [[GlnR]], [[GltC]], [[TnrA]]
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* Additional transcriptional regulators: [[AhrC]], [[RocR]], [[CcpA]], [[Fur]]
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* Control of ammonium uptake: [[NrgB|GlnK]]
  
== Additional stuff ==
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= Relevant ''Subti''Wiki pages =  
<pubmed> 14600241 20933603 </pubmed>
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* [[Biosynthesis/ acquisition of amino acids]]
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* [[Utilization of amino acids]]
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* [[TnrA regulon]]
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* [[GlnR regulon]]
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* [[GltC regulon]]
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* [[Trigger enzymes]]
  
== Methods ==
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= Glutamate metabolism in [[SubtiPathways]]: [http://subtiwiki.uni-goettingen.de/pathways/glutamate.html Ammonium/ glutamate] =
<pubmed> 17994626 </pubmed>
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= Additional websites =
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* [http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE34383&submit.x=22&submit.y=9 transcriptome analysis of a ''[[rocG]] [[gudB]]'' mutant vs. wild type]
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= Labs studying glutamate metabolism=
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* [[Fabian Commichau]], Göttingen, Germany
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* [[Susan Fisher]], Boston
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* [[Linc Sonenshein]], Boston
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* [[Jörg Stülke]], Göttingen
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= Important publications =
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==Reviews==
 +
<pubmed>18086213,17982469,16458044,10231480 22625175</pubmed>
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== Important original publications ==
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<pubmed>23811508 </pubmed>

Latest revision as of 10:44, 6 May 2021

Proteins involved in glutamate metabolism

Transport systems

Metabolic enzymes

Regulators

  • Key transcriptional regulators of nitrogen metabolism: GlnR, GltC, TnrA
  • Additional transcriptional regulators: AhrC, RocR, CcpA, Fur
  • Control of ammonium uptake: GlnK

Relevant SubtiWiki pages

Glutamate metabolism in SubtiPathways: Ammonium/ glutamate

Additional websites

Labs studying glutamate metabolism

Important publications

Reviews

Important original publications

Anne Krog, Tonje Marita Bjerkan Heggeset, Trond Erling Ellingsen, Trygve Brautaset
Functional characterization of key enzymes involved in L-glutamate synthesis and degradation in the thermotolerant and methylotrophic bacterium Bacillus methanolicus.
Appl Environ Microbiol: 2013, 79(17);5321-8
[PubMed:23811508] [WorldCat.org] [DOI] (I p)