Difference between revisions of "Metabolism of signalling nucleotides"
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* [[PgpH]] | * [[PgpH]] | ||
− | ===c-di-GMP | + | ===Protein potentially involved in c-di-GMP metabolism and signalling== |
+ | |||
+ | ==== Proteins containing a GGDEF domain (potential diguanylate cyclases) ==== | ||
+ | * [[DgcK]], has cyclase activity | ||
+ | * [[DgcW]], has cyclase activity, contains both a GGDEF and an EAL domain | ||
+ | * [[DgcP]], has cyclase activity | ||
+ | * [[YdaK]], no activity, modified GGDEF domain | ||
+ | * [[GdpP]], no diguanylate cyclase activity, is c-di-AMP specific phosphodiesterase (see above), modified GGDEF domain | ||
+ | |||
+ | ==== Proteins containing an EAL domain (potential c-di-GMP phosphodiesterases) ==== | ||
* [[DgcW]] (not experimentally proven) | * [[DgcW]] (not experimentally proven) | ||
* [[PdeH]] | * [[PdeH]] | ||
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− | |||
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=== Targets of signalling nucleotides === | === Targets of signalling nucleotides === |
Revision as of 09:41, 5 July 2016
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Contents
Genes in this functional category
ppGpp synthesis and degradation
c-di-AMP synthesis
Control of c-di-AMP synthesis
Note that c-di-AMP is essential for the growth of B. subtilis, but accumulation of the nucleotide is detrimental as well PubMed
c-di-AMP degradation
=Protein potentially involved in c-di-GMP metabolism and signalling
Proteins containing a GGDEF domain (potential diguanylate cyclases)
- DgcK, has cyclase activity
- DgcW, has cyclase activity, contains both a GGDEF and an EAL domain
- DgcP, has cyclase activity
- YdaK, no activity, modified GGDEF domain
- GdpP, no diguanylate cyclase activity, is c-di-AMP specific phosphodiesterase (see above), modified GGDEF domain
Proteins containing an EAL domain (potential c-di-GMP phosphodiesterases)
Targets of signalling nucleotides
- c-di-GMP targets
- DgrA (contains a PilZ domain)
Important original publications
Important reviews