Difference between revisions of "RecR"

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(Original publications)
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<pubmed> 22933559 </pubmed>
 
<pubmed> 22933559 </pubmed>
 
== Original publications ==
 
== Original publications ==
<pubmed>12884008,17581636, 16479537 24285298 24285298 24891441</pubmed>
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<pubmed>12884008,17581636, 16479537 24285298 24285298 24891441     9108290</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:09, 10 August 2015

  • Description: required for the formation of RecA DNA repair centers

Gene name recR
Synonyms recM
Essential no
Product formation of RecA DNA repair centers
Function DNA repair/ recombination
Gene expression levels in SubtiExpress: recR
Interactions involving this protein in SubtInteract: RecR
MW, pI 21 kDa, 5.301
Gene length, protein length 594 bp, 198 aa
Immediate neighbours yaaK, yaaL
Sequences Protein DNA DNA_with_flanks
Genetic context
RecR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RecR expression.png















Categories containing this gene/protein

DNA repair/ recombination

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU00210

Phenotypes of a mutant

  • drastically reduced survival of mature dormant spores after exposure to ultrahigh vacuum desiccation and ionizing radiation that induce single strand (ss) DNA nicks and double-strand breaks (DSBs) PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • required for the formation of RecA DNA repair centers (together with RecO) PubMed
  • Protein family: recR family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Justin S Lenhart, Jeremy W Schroeder, Brian W Walsh, Lyle A Simmons
DNA repair and genome maintenance in Bacillus subtilis.
Microbiol Mol Biol Rev: 2012, 76(3);530-64
[PubMed:22933559] [WorldCat.org] [DOI] (I p)

Original publications