Difference between revisions of "PhoR"

From SubtiWiki
Jump to: navigation, search
Line 135: Line 135:
  
 
* '''Additional information:'''
 
* '''Additional information:'''
 +
** number of protein molecules per cell (complex medium with amino acids, without glucose): 453 {{PubMed|24696501}}
  
 
=Biological materials =
 
=Biological materials =

Revision as of 10:09, 17 April 2014

  • Description: two-component sensor kinase, regulation of phosphate metabolism

Gene name phoR
Synonyms
Essential no
Product two-component sensor kinase
Function regulation of phosphate metabolism
Gene expression levels in SubtiExpress: phoR
Interactions involving this protein in SubtInteract: PhoR
MW, pI 64 kDa, 5.957
Gene length, protein length 1737 bp, 579 aa
Immediate neighbours polA, phoP
Sequences Protein DNA DNA_with_flanks
Genetic context
PhoR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PhoR expression.png
























Categories containing this gene/protein

phosphate metabolism, protein modification, transcription factors and their control, sporulation proteins, general stress proteins (controlled by SigB), membrane proteins, phosphoproteins

This gene is a member of the following regulons

CcpA regulon, PhoP regulon, SigB regulon, SigE regulon

The gene

Basic information

  • Locus tag: BSU29100

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of PhoP
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3CWF (extracellular PAS domain) PubMed
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • carbon catabolite repression (CcpA) PubMed
    • expressed under conditions of phosphate limitation (PhoP) PubMed
    • expressed in post-exponential phase (ScoC) PubMed
  • Additional information:
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 453 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Marion Hulett, University of Illinois at Chicago, USA Homepage

Your additional remarks

References