Difference between revisions of "EtfA"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU28520&redirect=T BSU28520] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/lcfA-ysiAB-etfBA.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/lcfA-ysiAB-etfBA.html] | ||
| Line 97: | Line 98: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU28520&redirect=T BSU28520] | ||
* '''Structure:''' | * '''Structure:''' | ||
Revision as of 14:27, 2 April 2014
- Description: electron transfer flavoprotein (alpha subunit)
| Gene name | etfA |
| Synonyms | |
| Essential | no |
| Product | electron transfer flavoprotein (alpha subunit) |
| Function | fatty acid degradation, calcium carbonate biomineralization |
| Gene expression levels in SubtiExpress: etfA | |
| Metabolic function and regulation of this protein in SubtiPathways: etfA | |
| MW, pI | 34 kDa, 4.652 |
| Gene length, protein length | 975 bp, 325 aa |
| Immediate neighbours | abf2, etfB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
electron transport/ other, utilization of lipids
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28520
Phenotypes of a mutant
Database entries
- BsubCyc: BSU28520
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ETF alpha-subunit/fixB family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions: EtfA-EtfB (based on function)
Database entries
- BsubCyc: BSU28520
- Structure:
- UniProt: P94551
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- induced by long-chain fatty acids (FadR) PubMed
- subject to carbon catabolite repression (CcpA-HPr(Ser-P) PubMed
- Regulatory mechanism:
- FadR: transcription repression PubMed
- CcpA-HPr(Ser-P): transcription repression PubMed
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Yasutaro Fujita, Hiroshi Matsuoka, Kazutake Hirooka
Regulation of fatty acid metabolism in bacteria.
Mol Microbiol: 2007, 66(4);829-39
[PubMed:17919287]
[WorldCat.org]
[DOI]
(P p)
Original Publications
Shigeo Tojo, Takenori Satomura, Hiroshi Matsuoka, Kazutake Hirooka, Yasutaro Fujita
Catabolite repression of the Bacillus subtilis FadR regulon, which is involved in fatty acid catabolism.
J Bacteriol: 2011, 193(10);2388-95
[PubMed:21398533]
[WorldCat.org]
[DOI]
(I p)
Massimiliano Marvasi, Pieter T Visscher, Brunella Perito, Giorgio Mastromei, Lilliam Casillas-Martínez
Physiological requirements for carbonate precipitation during biofilm development of Bacillus subtilis etfA mutant.
FEMS Microbiol Ecol: 2010, 71(3);341-50
[PubMed:20059546]
[WorldCat.org]
[DOI]
(I p)
Hiroshi Matsuoka, Kazutake Hirooka, Yasutaro Fujita
Organization and function of the YsiA regulon of Bacillus subtilis involved in fatty acid degradation.
J Biol Chem: 2007, 282(8);5180-94
[PubMed:17189250]
[WorldCat.org]
[DOI]
(P p)
Chiara Barabesi, Alessandro Galizzi, Giorgio Mastromei, Mila Rossi, Elena Tamburini, Brunella Perito
Bacillus subtilis gene cluster involved in calcium carbonate biomineralization.
J Bacteriol: 2007, 189(1);228-35
[PubMed:17085570]
[WorldCat.org]
[DOI]
(P p)
