YrvJ

• Description: similar to N-acetylmuramoyl-L-alanine amidase
  
  

Gene name	yrvJ
Synonyms
Essential	no
Product	peptidoglycan hydrolase
Function	cell wall metabolism
Gene expression levels in SubtiExpress: yrvJ
MW, pI	55 kDa, 5.192
Gene length, protein length	1554 bp, 518 aa
Immediate neighbours	yrzK, dtd
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall/ other

The gene

Basic information

• Locus tag: BSU27580

Database entries

• BsubCyc: BSU27580

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot)

• Protein family: N-acetylmuramoyl-L-alanine amidase 3 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: contains an amidase_3 domain (like CwlC, CwlD, LytC, YqiI)

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU27580

• Structure:

• UniProt: O32041

• KEGG entry: [3]

• E.C. number: 3.5.1.28

Expression and regulation

• Operon: yrvJ PubMed

• Expression browser: yrvJ PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

T M Wendrich, M A Marahiel
Cloning and characterization of a relA/spoT homologue from Bacillus subtilis.
Mol Microbiol: 1997, 26(1);65-79
[PubMed:9383190] [WorldCat.org] [DOI] (P p)