Difference between revisions of "LtaS"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU07710&redirect=T BSU07710] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yflE.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yflE.html] | ||
| Line 96: | Line 97: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU07710&redirect=T BSU07710] | ||
* '''Structure:''' [http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?Dopt=s&uid=69910&ordinalpos=1&log$=structuread_title 2W8D] | * '''Structure:''' [http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?Dopt=s&uid=69910&ordinalpos=1&log$=structuread_title 2W8D] | ||
Revision as of 13:12, 2 April 2014
- Description: polyglycerolphosphate lipoteichoic acid synthase
| Gene name | ltaS |
| Synonyms | yflE |
| Essential | no |
| Product | major lipoteichoic acid synthase |
| Function | biosynthesis of lipoteichoic acid |
| Gene expression levels in SubtiExpress: ltaS | |
| Metabolic function and regulation of this protein in SubtiPathways: ltaS | |
| MW, pI | 74 kDa, 5.202 |
| Gene length, protein length | 1947 bp, 649 aa |
| Immediate neighbours | nagP, yflD |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis of cell wall components, membrane proteins, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- BsubCyc: BSU07710
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: LTA synthase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylated on Thr-297 PubMed
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU07710
- Structure: 2W8D
- UniProt: O34952
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: ltaS (according to DBTBS)
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- GP1389 ltaS::aphA3, available in Jörg Stülke's lab
- GP1396 ltaS::tet, available in Jörg Stülke's lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Nathalie T Reichmann, Angelika Gründling
Location, synthesis and function of glycolipids and polyglycerolphosphate lipoteichoic acid in Gram-positive bacteria of the phylum Firmicutes.
FEMS Microbiol Lett: 2011, 319(2);97-105
[PubMed:21388439]
[WorldCat.org]
[DOI]
(I p)
Iain C Sutcliffe
Priming and elongation: dissection of the lipoteichoic acid biosynthetic pathway in Gram-positive bacteria.
Mol Microbiol: 2011, 79(3);553-6
[PubMed:21255102]
[WorldCat.org]
[DOI]
(I p)
Original publications
