Difference between revisions of "GabD"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU03910&redirect=T BSU03910] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/gabTD.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/gabTD.html] | ||
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU03910&redirect=T BSU03910] | ||
* '''Structure:''' [http://www.pdb.org/pdb/explore/explore.do?structureId=3RHH 3RHH] (from from ''Bacillus halodurans'' C-125 complexed with NADP, 36% identity, 68% similarity) | * '''Structure:''' [http://www.pdb.org/pdb/explore/explore.do?structureId=3RHH 3RHH] (from from ''Bacillus halodurans'' C-125 complexed with NADP, 36% identity, 68% similarity) | ||
Revision as of 12:59, 2 April 2014
- Description: succinate-semialdehyde dehydrogenase (NADP), general stress protein
| Gene name | gabD |
| Synonyms | ycnH |
| Essential | no |
| Product | succinate-semialdehyde dehydrogenase (NADP) |
| Function | utilization of gamma-amino butyric acid |
| Gene expression levels in SubtiExpress: gabD | |
| MW, pI | 50 kDa, 4.763 |
| Gene length, protein length | 1386 bp, 462 aa |
| Immediate neighbours | gabT, glcU |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
utilization of amino acids, general stress proteins (controlled by SigB)
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU03910
Phenotypes of a mutant
- growth defect in the presence of gamma-aminobutyrate PubMed
Database entries
- BsubCyc: BSU03910
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU03910
- Structure: 3RHH (from from Bacillus halodurans C-125 complexed with NADP, 36% identity, 68% similarity)
- UniProt: P94428
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Linc Sonenshein, Tufts University, Boston, MA, USA Homepage
Your additional remarks
References
Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528]
[WorldCat.org]
[DOI]
(P p)
Boris R Belitsky
Bacillus subtilis GabR, a protein with DNA-binding and aminotransferase domains, is a PLP-dependent transcriptional regulator.
J Mol Biol: 2004, 340(4);655-64
[PubMed:15223311]
[WorldCat.org]
[DOI]
(P p)
Boris R Belitsky, Abraham L Sonenshein
GabR, a member of a novel protein family, regulates the utilization of gamma-aminobutyrate in Bacillus subtilis.
Mol Microbiol: 2002, 45(2);569-83
[PubMed:12123465]
[WorldCat.org]
[DOI]
(P p)
A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224]
[WorldCat.org]
[DOI]
(P p)
