Difference between revisions of "HelD"

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(Database entries)
Line 83: Line 83:
  
 
* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
** HelD interacts with the [[RNA polymerase]] {{PubMed|21710567}}
+
** HelD interacts with the [[RNA polymerase]] core enzyme {{PubMed|24520113,21710567}}
  
 
* '''[[Localization]]:''' cytoplasm (according to Swiss-Prot)
 
* '''[[Localization]]:''' cytoplasm (according to Swiss-Prot)

Revision as of 09:55, 13 February 2014

  • Description: DNA 3'-5' helicase IV, stimulates transcription in an ATP-dependent manner by enhancing transcriptional cycling and elongation

Gene name helD
Synonyms yvgS
Essential no
Product DNA 3'-5' helicase IV
Function transcription, DNA repair/ recombination
Gene expression levels in SubtiExpress: helD
MW, pI 89 kDa, 6.083
Gene length, protein length 2322 bp, 774 aa
Immediate neighbours cysI, yvgT
Sequences Protein DNA DNA_with_flanks
Genetic context
YvgS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
HelD expression.png















Categories containing this gene/protein

DNA repair/ recombination, transcription

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU33450

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: UvrD subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure: 3DMN (C-terminal domain of the protein from Lactobacillus plantarum, 39% identity)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
    • 1A899 ( helD::erm), available at BGSC
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References