Difference between revisions of "WprA"

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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
 
** important for [[TatAY]]-[[TatCY]]-dependent export of [[YkuE]] and [[YwbN]] {{PubMed|23180473}}
 
** important for [[TatAY]]-[[TatCY]]-dependent export of [[YkuE]] and [[YwbN]] {{PubMed|23180473}}
 +
** involved in degradation of [[PrsA]], [[HtrA]], and [[HtrB]] {{PubMed|24362423}}
  
 
* '''Protein family:''' peptidase S8 family (according to Swiss-Prot)
 
* '''Protein family:''' peptidase S8 family (according to Swiss-Prot)
Line 145: Line 146:
  
 
=References=
 
=References=
<pubmed> 22900538 22923395 23180473 21815947 10075409,11987133,9004506,20525796,18957862 18763711 16306698, 9687444 12028417 </pubmed>
+
<pubmed> 22900538 22923395 23180473 21815947 10075409,11987133,9004506,20525796,18957862 18763711 16306698, 9687444 12028417 24362423</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:31, 16 January 2014

  • Description: secreted quality control protease

Gene name wprA
Synonyms yisM
Essential no
Product secreted quality control protease
Function protein quality control
Gene expression levels in SubtiExpress: wprA
Interactions involving this protein in SubtInteract: WprA
MW, pI 96 kDa, 9.58
Gene length, protein length 2682 bp, 894 aa
Immediate neighbours yisL, yisN
Sequences Protein DNA DNA_with_flanks
Genetic context
WprA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
WprA expression.png















Categories containing this gene/protein

cell wall/ other, proteolysis,

This gene is a member of the following regulons

YvrHb regulon, CcpA regulon

The gene

Basic information

  • Locus tag: BSU10770

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Protein family: peptidase S8 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References