Difference between revisions of "DeoR"

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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU39430 deoR]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU39430 deoR]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/nucleosides_catabolism.html Nucleoside catabolism], [http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=deoR deoR]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 35 kDa, 6   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 35 kDa, 6   

Revision as of 12:01, 7 January 2014

  • Description: transcriptional repressor of the dra-nupC-pdp operon

Gene name deoR
Synonyms yxxC
Essential no
Product transcriptional repressor
Function regulation of deoxyribonucleotide utilization
Gene expression levels in SubtiExpress: deoR
Metabolic function and regulation of this protein in SubtiPathways:
deoR
MW, pI 35 kDa, 6
Gene length, protein length 939 bp, 313 aa
Immediate neighbours dra, yxxB
Sequences Protein DNA DNA_with_flanks
Genetic context
DeoR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DeoR expression.png




























Categories containing this gene/protein

utilization of nucleotides, transcription factors and their control

This gene is a member of the following regulons

The DeoR regulon:

The gene

Basic information

  • Locus tag: BSU39430

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transcription repression of the dra-nupC-pdp operon
  • Protein family: sorC transcriptional regulatory family (according to Swiss-Prot) DeoR family of transcription repressors
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

X Zeng, H H Saxild, R L Switzer
Purification and characterization of the DeoR repressor of Bacillus subtilis.
J Bacteriol: 2000, 182(7);1916-22
[PubMed:10714997] [WorldCat.org] [DOI] (P p)

X Zeng, H H Saxild
Identification and characterization of a DeoR-specific operator sequence essential for induction of dra-nupC-pdp operon expression in Bacillus subtilis.
J Bacteriol: 1999, 181(6);1719-27
[PubMed:10074062] [WorldCat.org] [DOI] (P p)

H H Saxild, L N Andersen, K Hammer
Dra-nupC-pdp operon of Bacillus subtilis: nucleotide sequence, induction by deoxyribonucleosides, and transcriptional regulation by the deoR-encoded DeoR repressor protein.
J Bacteriol: 1996, 178(2);424-34
[PubMed:8550462] [WorldCat.org] [DOI] (P p)