Difference between revisions of "MenE"

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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30790 menE]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30790 menE]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/menaquinone.html Menaquinone]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=menE menE]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 54 kDa, 5.466   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 54 kDa, 5.466   

Revision as of 11:31, 7 January 2014

  • Description: o-succinylbenzoate-CoA ligase

Gene name menE
Synonyms
Essential yes PubMed
Product o-succinylbenzoate-CoA ligase
Function biosynthesis of menaquinone
Gene expression levels in SubtiExpress: menE
Metabolic function and regulation of this protein in SubtiPathways:
menE
MW, pI 54 kDa, 5.466
Gene length, protein length 1458 bp, 486 aa
Immediate neighbours menC, menB
Sequences Protein DNA DNA_with_flanks
Genetic context
MenE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MenE expression.png




























Categories containing this gene/protein

biosynthesis of cofactors, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU30790

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + 2-succinylbenzoate + CoA = AMP + diphosphate + 2-succinylbenzoyl-CoA (according to Swiss-Prot)
  • Protein family: MenE type 1 subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References