Difference between revisions of "LipC"
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| − | * '''Description:''' phospholipase implicated in spore germination <br/><br/> | + | * '''Description:''' spore coat protein, phospholipase implicated in spore germination <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Product''' || spore coat phospholipase B | |style="background:#ABCDEF;" align="center"| '''Product''' || spore coat phospholipase B | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || spore germination | + | |style="background:#ABCDEF;" align="center"|'''Function''' || spore [[germination]] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU04110 lipC] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU04110 lipC] | ||
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<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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{{SubtiWiki regulon|[[KipR regulon]]}}, | {{SubtiWiki regulon|[[KipR regulon]]}}, | ||
{{SubtiWiki regulon|[[SigK regulon]]}}, | {{SubtiWiki regulon|[[SigK regulon]]}}, | ||
| − | {{SubtiWiki regulon|[[TnrA regulon]]}} | + | {{SubtiWiki regulon|[[TnrA regulon]]}}, |
| + | {{SubtiWiki regulon|[[GerE regulon]]}} | ||
| + | |||
=The gene= | =The gene= | ||
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | defective in L-alanine-stimulated germination {{PubMed|20057119}} | + | * defective in L-alanine-stimulated germination {{PubMed|20057119}} |
| + | |||
=== Database entries === | === Database entries === | ||
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=== Additional information=== | === Additional information=== | ||
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* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| − | ** spore coat {{PubMed|17220230,20057119}} | + | ** spore coat (basement), localization depends on [[SpoIVA]] {{PubMed|22171814,17220230,20057119}} |
=== Database entries === | === Database entries === | ||
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=References= | =References= | ||
| − | <pubmed> 17220230 9334321 20057119 </pubmed> | + | <pubmed> 17220230 9334321 20057119 22171814</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:56, 13 August 2013
- Description: spore coat protein, phospholipase implicated in spore germination
| Gene name | lipC |
| Synonyms | ycsK |
| Essential | no |
| Product | spore coat phospholipase B |
| Function | spore germination |
| Gene expression levels in SubtiExpress: lipC | |
| Function and regulation of this protein in SubtiPathways: Phosphorelay | |
| MW, pI | 23 kDa, 5.839 |
| Gene length, protein length | 639 bp, 213 aa |
| Immediate neighbours | kipR, yczI |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
utilization of lipids, sporulation proteins, germination
This gene is a member of the following regulons
KipR regulon, SigK regulon, TnrA regulon, GerE regulon
The gene
Basic information
- Locus tag: BSU04110
Phenotypes of a mutant
- defective in L-alanine-stimulated germination PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: cleaves the fatty acids at the sn-1 and sn-2 positions of phospholipids PubMed
- Protein family: 'GDSL' lipolytic enzyme family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P42969
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Peter T McKenney, Patrick Eichenberger
Dynamics of spore coat morphogenesis in Bacillus subtilis.
Mol Microbiol: 2012, 83(2);245-60
[PubMed:22171814]
[WorldCat.org]
[DOI]
(I p)
Atsushi Masayama, Shiro Kato, Takuya Terashima, Anne Mølgaard, Hisashi Hemmi, Tohru Yoshimura, Ryuichi Moriyama
Bacillus subtilis spore coat protein LipC is a phospholipase B.
Biosci Biotechnol Biochem: 2010, 74(1);24-30
[PubMed:20057119]
[WorldCat.org]
[DOI]
(I p)
Atsushi Masayama, Ritsuko Kuwana, Hiromu Takamatsu, Hisashi Hemmi, Tohru Yoshimura, Kazuhito Watabe, Ryuichi Moriyama
A novel lipolytic enzyme, YcsK (LipC), located in the spore coat of Bacillus subtilis, is involved in spore germination.
J Bacteriol: 2007, 189(6);2369-75
[PubMed:17220230]
[WorldCat.org]
[DOI]
(P p)
L Wang, R Grau, M Perego, J A Hoch
A novel histidine kinase inhibitor regulating development in Bacillus subtilis.
Genes Dev: 1997, 11(19);2569-79
[PubMed:9334321]
[WorldCat.org]
[DOI]
(P p)
