Difference between revisions of "YhfU"

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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 
+
{{SubtiWiki regulon|[[BirA regulon]]}}
  
 
=The gene=
 
=The gene=
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* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** repressed in the presence of biotin ([[BirA]]) {{PubMed|11717296}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[BirA]]: transcription repression {{PubMed|11717296}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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<pubmed>21437340, 20497229, </pubmed>
 
<pubmed>21437340, 20497229, </pubmed>
 
== Original publications ==  
 
== Original publications ==  
<pubmed>18763711, 17301237 </pubmed>
+
<pubmed>18763711, 17301237 11717296</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:13, 13 July 2013

Gene name yhfU
Synonyms bioY
Essential no
Product S protein of biotin ECF transporter
Function uptake of biotin
Gene expression levels in SubtiExpress: yhfU
MW, pI 19 kDa, 10.681
Gene length, protein length 558 bp, 186 aa
Immediate neighbours yhfT, hemAT
Sequences Protein DNA DNA_with_flanks
Genetic context
YhfU context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YhfU expression.png















Categories containing this gene/protein

ECF transporter, biosynthesis of cofactors, membrane proteins

This gene is a member of the following regulons

BirA regulon

The gene

Basic information

  • Locus tag: BSU10370

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: uptake of biotin PubMed
  • Protein family: bioY family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • repressed in the presence of biotin (BirA) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Steven Lin, John E Cronan
Closing in on complete pathways of biotin biosynthesis.
Mol Biosyst: 2011, 7(6);1811-21
[PubMed:21437340] [WorldCat.org] [DOI] (I p)

Thomas Eitinger, Dmitry A Rodionov, Mathias Grote, Erwin Schneider
Canonical and ECF-type ATP-binding cassette importers in prokaryotes: diversity in modular organization and cellular functions.
FEMS Microbiol Rev: 2011, 35(1);3-67
[PubMed:20497229] [WorldCat.org] [DOI] (I p)

Original publications