Difference between revisions of "RapH"

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Revision as of 12:43, 16 May 2013

Gene name rapH
Synonyms yeeH, yzqA
Essential no
Product response regulator aspartate phosphatase
Function control of sporulation initiation and ComA activity
Gene expression levels in SubtiExpress: rapH
Interactions involving this protein in SubtInteract: RapH
Function and regulation of this protein in SubtiPathways:
Phosphorelay
MW, pI 49 kDa, 6.121
Gene length, protein length 1293 bp, 431 aa
Immediate neighbours yeeG, phrH
Sequences Protein DNA DNA_with_flanks
Genetic context
RapH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RapH expression.png




























Categories containing this gene/protein

protein modification, transcription factors and their control, phosphorelay, quorum sensing

This gene is a member of the following regulons

AbrB regulon, ComK regulon, RghR regulon

The gene

Basic information

  • Locus tag: BSU06830

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • binds to and thereby inhibits ComA activity PubMed
    • RapH dephosphorylates Spo0F-P and thereby controls the phosphorelay PubMed
    • in addition to dephosphorylating Spo0F, RapH can antagonize sporulation by sterically blocking phosphoryl transfer to and from Spo0F PubMed
  • Protein family: RAP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed