Difference between revisions of "PyrR"
| Line 24: | Line 24: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylyB]]'', ''[[pyrP]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylyB]]'', ''[[pyrP]]'' | ||
|- | |- | ||
| − | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15470 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15470 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15470 | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15470 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15470 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15470 DNA_with_flanks] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:pyrR_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:pyrR_context.gif]] | ||
Revision as of 10:10, 14 May 2013
- Description: transcriptional antiterminator of the pyr operon
| Gene name | pyrR |
| Synonyms | |
| Essential | no |
| Product | transcriptional antiterminator with minor uracil phosphoribosyltransferase activity |
| Function | regulation of pyrimidine biosynthesis |
| Gene expression levels in SubtiExpress: pyrR | |
| Metabolic function and regulation of this protein in SubtiPathways: Pyrimidines, Nucleotides (regulation) | |
| MW, pI | 20 kDa, 4.991 |
| Gene length, protein length | 543 bp, 181 aa |
| Immediate neighbours | ylyB, pyrP |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
- 1 Categories containing this gene/protein
- 2 This gene is a member of the following regulons
- 3 The PyrR regulon: pyrR-pyrP-pyrB-pyrC-pyrAA-pyrAB-pyrK-pyrD-pyrF-pyrE
- 4 The gene
- 5 The protein
- 6 Expression and regulation
- 7 Biological materials
- 8 Labs working on this gene/protein
- 9 Your additional remarks
- 10 References
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, transcription factors and their control, RNA binding regulators
This gene is a member of the following regulons
The PyrR regulon: pyrR-pyrP-pyrB-pyrC-pyrAA-pyrAB-pyrK-pyrD-pyrF-pyrE
The gene
Basic information
- Locus tag: BSU15470
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate (according to Swiss-Prot)
- Protein family: PyrR subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 1A3C (dimeric form)
- UniProt: P39765
- KEGG entry: [3]
- E.C. number: 2.4.2.9
Additional information
Expression and regulation
- Regulatory mechanism:
- PyrR: RNA switch, transcription termination/ antitermination (in the presence of uridine nucleotides: termination, in their absence: antitermination) PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
