Difference between revisions of "CtaO"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yjdJ]]'', ''[[cotT]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yjdJ]]'', ''[[cotT]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU12080 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU12080 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU12080 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU12080 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU12080 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU12080 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ctaO_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ctaO_context.gif]]

Revision as of 09:57, 14 May 2013

  • Description: heme O synthase (minor enzyme)

Gene name ctaO
Synonyms yjdK
Essential no
Product heme O synthase (minor enzyme)
Function heme biosynthesis
Gene expression levels in SubtiExpress: ctaO
MW, pI 36 kDa, 10.121
Gene length, protein length 987 bp, 329 aa
Immediate neighbours yjdJ, cotT
Sequences Protein DNA DNA_with_flanks
Genetic context
CtaO context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CtaO expression.png

























Categories containing this gene/protein

biosynthesis of cofactors, membrane proteins

This gene is a member of the following regulons

AbrB regulon

The gene

Basic information

  • Locus tag: BSU12080

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: Protoheme IX farnesyltransferase subfamily (according to Swiss-Prot)
  • Paralogous protein(s): CtaB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • the amount of the mRNA is substantially decreased upon depletion of RNase Y PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947

M Throne-Holst, L Hederstedt
The Bacillus subtilis ctaB paralogue, yjdK, can complement the heme A synthesis deficiency of a CtaB-deficient mutant.
FEMS Microbiol Lett: 2000, 183(2);247-51
[PubMed:10675592] [WorldCat.org] [DOI] (P p)