Difference between revisions of "AlbA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || antilisterial bacteriocin (subtilosin) production | |style="background:#ABCDEF;" align="center"|'''Function''' || antilisterial bacteriocin (subtilosin) production | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU37370 albA] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 51 kDa, 6.195 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 51 kDa, 6.195 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sboX]]'', ''[[albB]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sboX]]'', ''[[albB]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU37370 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU37370 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU37370 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:albA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:albA_context.gif]] | ||
Revision as of 14:07, 13 May 2013
- Description: radical S-adenosylmethionine enzyme, antilisterial bacteriocin (subtilosin) production
| Gene name | albA |
| Synonyms | ywiA |
| Essential | no |
| Product | radical S-adenosylmethionine enzyme |
| Function | antilisterial bacteriocin (subtilosin) production |
| Gene expression levels in SubtiExpress: albA | |
| MW, pI | 51 kDa, 6.195 |
| Gene length, protein length | 1344 bp, 448 aa |
| Immediate neighbours | sboX, albB |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds
This gene is a member of the following regulons
AbrB regulon, ResD regulon, Rok regulon
The gene
Basic information
- Locus tag: BSU37370
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- catalyzes thioether bond formation in subtilosin A PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): contains two [4Fe-4S] clusters PubMed
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P71011
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
Mark A Strauch, Benjamin G Bobay, John Cavanagh, Fude Yao, Angelo Wilson, Yoann Le Breton
Abh and AbrB control of Bacillus subtilis antimicrobial gene expression.
J Bacteriol: 2007, 189(21);7720-32
[PubMed:17720793]
[WorldCat.org]
[DOI]
(P p)
Paul D Straight, Michael A Fischbach, Christopher T Walsh, David Z Rudner, Roberto Kolter
A singular enzymatic megacomplex from Bacillus subtilis.
Proc Natl Acad Sci U S A: 2007, 104(1);305-10
[PubMed:17190806]
[WorldCat.org]
[DOI]
(P p)
Mark Albano, Wiep Klaas Smits, Linh T Y Ho, Barbara Kraigher, Ines Mandic-Mulec, Oscar P Kuipers, David Dubnau
The Rok protein of Bacillus subtilis represses genes for cell surface and extracellular functions.
J Bacteriol: 2005, 187(6);2010-9
[PubMed:15743949]
[WorldCat.org]
[DOI]
(P p)
M M Nakano, G Zheng, P Zuber
Dual control of sbo-alb operon expression by the Spo0 and ResDE systems of signal transduction under anaerobic conditions in Bacillus subtilis.
J Bacteriol: 2000, 182(11);3274-7
[PubMed:10809710]
[WorldCat.org]
[DOI]
(P p)
G Zheng, R Hehn, P Zuber
Mutational analysis of the sbo-alb locus of Bacillus subtilis: identification of genes required for subtilosin production and immunity.
J Bacteriol: 2000, 182(11);3266-73
[PubMed:10809709]
[WorldCat.org]
[DOI]
(P p)
G Zheng, L Z Yan, J C Vederas, P Zuber
Genes of the sbo-alb locus of Bacillus subtilis are required for production of the antilisterial bacteriocin subtilosin.
J Bacteriol: 1999, 181(23);7346-55
[PubMed:10572140]
[WorldCat.org]
[DOI]
(P p)
