Difference between revisions of "CypX"
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of the extracellular iron chelate pulcherrimin | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of the extracellular iron chelate pulcherrimin | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35060 cypX] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 5.306 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 5.306 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yvnA]]'', ''[[yvmC]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yvnA]]'', ''[[yvmC]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35060 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35060 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35060 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:cypX_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:cypX_context.gif]] | ||
Revision as of 13:57, 13 May 2013
- Description: cytochrome P450, cyclo-l-leucyl-l-leucyl dipeptide oxidase
| Gene name | cypX |
| Synonyms | |
| Essential | no |
| Product | cytochrome P450, cyclo-l-leucyl-l-leucyl dipeptide oxidase |
| Function | biosynthesis of the extracellular iron chelate pulcherrimin |
| Gene expression levels in SubtiExpress: cypX | |
| MW, pI | 45 kDa, 5.306 |
| Gene length, protein length | 1215 bp, 405 aa |
| Immediate neighbours | yvnA, yvmC |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
acquisition of iron, electron transport/ other, iron metabolism
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35060
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- implicated in the three-step oxidative transformation of the diketopiperazine cyclo-l-leucyl-l-leucyl into pulcherriminic acid PubMed
- Protein family: cytochrome P450 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: O34926
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
Max J Cryle, Stephen G Bell, Ilme Schlichting
Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase.
Biochemistry: 2010, 49(34);7282-96
[PubMed:20690619]
[WorldCat.org]
[DOI]
(I p)
R L Uffen, E Canale-Parola
Synthesis of pulcherriminic acid by Bacillus subtilis.
J Bacteriol: 1972, 111(1);86-93
[PubMed:4204912]
[WorldCat.org]
[DOI]
(P p)
