Difference between revisions of "AzlC"

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|style="background:#ABCDEF;" align="center"|'''Function''' || branched-chain amino acid transport
 
|style="background:#ABCDEF;" align="center"|'''Function''' || branched-chain amino acid transport
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU26710 azlC]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU26710 azlC]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_syn.html Lipid synthesis], [http://subtiwiki.uni-goettingen.de/pathways/ile_val_leu.html Ile, Leu, Val]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_syn.html Lipid synthesis], [http://subtiwiki.uni-goettingen.de/pathways/ile_val_leu.html Ile, Leu, Val]'''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[azlD]]'', ''[[azlB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[azlD]]'', ''[[azlB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14612&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU26710 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU26710 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU26710 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:azlC_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:azlC_context.gif]]

Revision as of 13:24, 13 May 2013

  • Description: branched-chain amino acid transport

Gene name azlC
Synonyms yrdH
Essential no
Product unknown
Function branched-chain amino acid transport
Gene expression levels in SubtiExpress: azlC
Metabolic function and regulation of this protein in SubtiPathways:
Lipid synthesis, Ile, Leu, Val
MW, pI 28 kDa, 9.73
Gene length, protein length 762 bp, 254 aa
Immediate neighbours azlD, azlB
Sequences Protein DNA Advanced_DNA
Genetic context
AzlC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AzlC expression.png





























Categories containing this gene/protein

transporters/ other, biosynthesis/ acquisition of amino acids, utilization of amino acids, membrane proteins

This gene is a member of the following regulons

AzlB regulon

The gene

Basic information

  • Locus tag: BSU26710

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: azlC family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulatory mechanism: AzlB: transcriptional repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

B R Belitsky, M C Gustafsson, A L Sonenshein, C Von Wachenfeldt
An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport.
J Bacteriol: 1997, 179(17);5448-57
[PubMed:9287000] [WorldCat.org] [DOI] (P p)