Difference between revisions of "ArsC"
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|style="background:#ABCDEF;" align="center"|'''Function''' || detoxification of arsenate | |style="background:#ABCDEF;" align="center"|'''Function''' || detoxification of arsenate | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25780 arsC] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ArsC ArsC] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ArsC ArsC] | ||
| Line 24: | Line 24: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoIVCA]]'', ''[[arsB]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoIVCA]]'', ''[[arsB]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25780 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25780 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25780 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:arsC_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:arsC_context.gif]] | ||
Revision as of 13:22, 13 May 2013
- Description: arsenate reductase
| Gene name | arsC |
| Synonyms | yqcM |
| Essential | no |
| Product | arsenate reductase |
| Function | detoxification of arsenate |
| Gene expression levels in SubtiExpress: arsC | |
| Interactions involving this protein in SubtInteract: ArsC | |
| MW, pI | 15 kDa, 4.749 |
| Gene length, protein length | 417 bp, 139 aa |
| Immediate neighbours | spoIVCA, arsB |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
resistance against toxic metals, Skin element
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU25780
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate (according to Swiss-Prot)
- Protein family: ArsC family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: P45947
- KEGG entry: [3]
- E.C. number: 3.1.3.48
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
You Li, Yunfei Hu, Xinxin Zhang, Huimin Xu, Ewen Lescop, Bin Xia, Changwen Jin
Conformational fluctuations coupled to the thiol-disulfide transfer between thioredoxin and arsenate reductase in Bacillus subtilis.
J Biol Chem: 2007, 282(15);11078-83
[PubMed:17303556]
[WorldCat.org]
[DOI]
(P p)
Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325]
[WorldCat.org]
[DOI]
(P p)
Z Guan, L Hederstedt, J Li, X D Su
Preparation and crystallization of a Bacillus subtilis arsenate reductase.
Acta Crystallogr D Biol Crystallogr: 2001, 57(Pt 11);1718-21
[PubMed:11679756]
[WorldCat.org]
[DOI]
(P p)
T Sato, Y Kobayashi
The ars operon in the skin element of Bacillus subtilis confers resistance to arsenate and arsenite.
J Bacteriol: 1998, 180(7);1655-61
[PubMed:9537360]
[WorldCat.org]
[DOI]
(P p)
Additional publications: PubMed
