Difference between revisions of "YisP"
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[KinC]] activity | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[KinC]] activity | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU10810 yisP] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 7.258 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 7.258 | ||
| Line 21: | Line 21: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yizA]]'', ''[[yisQ]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yizA]]'', ''[[yisQ]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU10810 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU10810 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU10810 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yisP_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yisP_context.gif]] | ||
Revision as of 12:30, 13 May 2013
- Description: production of squalene-derived polyisoprenoids
| Gene name | yisP |
| Synonyms | yucD |
| Essential | no |
| Product | squalene synthase |
| Function | control of KinC activity |
| Gene expression levels in SubtiExpress: yisP | |
| MW, pI | 31 kDa, 7.258 |
| Gene length, protein length | 822 bp, 274 aa |
| Immediate neighbours | yizA, yisQ |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis of lipids, phosphorelay, biofilm formation
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU10810
Phenotypes of a mutant
- complete loss of pellicle-forming ability PubMed
- reduced protein secretion PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): NADH PubMed
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O06728
- KEGG entry: [2]
- E.C. number:
Additional information
The gene is annotated in KEGG as an ortholog of phytoene synthase EC 2.5.1.32. No EC annotation is available in Swiss-Prot/MetaCSwiss-Prot/MetaCyc.literature/experimental evidence supporting the annotation is available. PubMed
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Juri Niño Bach, Marc Bramkamp
Flotillins functionally organize the bacterial membrane.
Mol Microbiol: 2013, 88(6);1205-17
[PubMed:23651456]
[WorldCat.org]
[DOI]
(I p)
Yumei Hu, Shiru Jia, Feifei Ren, Chun Hsiang Huang, Tzu Ping Ko, Douglas A Mitchell, Rey Ting Guo, Yingying Zheng
Crystallization and preliminary X-ray diffraction analysis of YisP protein from Bacillus subtilis subsp. subtilis strain 168.
Acta Crystallogr Sect F Struct Biol Cryst Commun: 2013, 69(Pt 1);77-9
[PubMed:23295493]
[WorldCat.org]
[DOI]
(I p)
Daniel López, Roberto Kolter
Functional microdomains in bacterial membranes.
Genes Dev: 2010, 24(17);1893-902
[PubMed:20713508]
[WorldCat.org]
[DOI]
(I p)
Tzu-Lin Hsiao, Olga Revelles, Lifeng Chen, Uwe Sauer, Dennis Vitkup
Automatic policing of biochemical annotations using genomic correlations.
Nat Chem Biol: 2010, 6(1);34-40
[PubMed:19935659]
[WorldCat.org]
[DOI]
(I p)
