yisQ

168

probable multidrug resistance protein

Locus: BSU_10820

Molecular weight: 49.85 kDa

Isoelectric point: 10.18

Protein length: 455 aa

Gene length: 1368 bp

Function: unknown

Product: putative multidrug exporter

Essential: no

Synonyms: yisQ, yucE

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG0534 (Galperin et al., 2021)

Gene

Coordinates: 1,160,776  1,162,143

The protein

Protein family

• MOP exporter family
• multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family (accordinig to UniProt)

Structure

• 3VVO (PDB) (MATE multidrug exporter from Pyrococcus furiosus, 23% identity) PubMed
• O07940 (AlphaFold)

Localization

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: yisQ

  Description: PubMed

Biological materials

Mutant

• MGNA-B182 (yisQ::erm), available at the NBRP B. subtilis, Japan
• BKE10820 (yisQ::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCGTGTCTAACCCCTTTC,  downstream forward: _UP4_TAACACCCGGCTCAATCAAG
• BKK10820 (yisQ::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCGTGTCTAACCCCTTTC,  downstream forward: _UP4_TAACACCCGGCTCAATCAAG

References

Research papers

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