Difference between revisions of "NiaP"
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|style="background:#ABCDEF;" align="center"|'''Function''' || uptake of niacin | |style="background:#ABCDEF;" align="center"|'''Function''' || uptake of niacin | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02950 niaP] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 9.502 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 9.502 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yceH]]'', ''[[yceJ]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yceH]]'', ''[[yceJ]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02950 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02950 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02950 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yceI_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yceI_context.gif]] | ||
Revision as of 12:05, 13 May 2013
- Description: nicotinate transporter
| Gene name | yceI |
| Synonyms | |
| Essential | no |
| Product | nicotinate transporter |
| Function | uptake of niacin |
| Gene expression levels in SubtiExpress: niaP | |
| MW, pI | 43 kDa, 9.502 |
| Gene length, protein length | 1200 bp, 400 aa |
| Immediate neighbours | yceH, yceJ |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transporters/ other, biosynthesis of cofactors, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU02950
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: MFS transporter PubMed
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: 10 membrane-spanning domains PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane PubMed
Database entries
- Structure:
- UniProt: O34691
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Linda Jeanguenin, Aurora Lara-Núñez, Dmitry A Rodionov, Andrei L Osterman, Nataliya Y Komarova, Doris Rentsch, Jesse F Gregory, Andrew D Hanson
Comparative genomics and functional analysis of the NiaP family uncover nicotinate transporters from bacteria, plants, and mammals.
Funct Integr Genomics: 2012, 12(1);25-34
[PubMed:21953179]
[WorldCat.org]
[DOI]
(I p)
Original publications
Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711]
[WorldCat.org]
[DOI]
(I p)
Dmitry A Rodionov, Xiaoqing Li, Irina A Rodionova, Chen Yang, Leonardo Sorci, Etienne Dervyn, Dariusz Martynowski, Hong Zhang, Mikhail S Gelfand, Andrei L Osterman
Transcriptional regulation of NAD metabolism in bacteria: genomic reconstruction of NiaR (YrxA) regulon.
Nucleic Acids Res: 2008, 36(6);2032-46
[PubMed:18276644]
[WorldCat.org]
[DOI]
(I p)
