Difference between revisions of "PabB"
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of folate | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of folate | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00740 pabB] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/PabB PabB] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/PabB PabB] | ||
| Line 26: | Line 26: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cysK]]'', ''[[pabA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cysK]]'', ''[[pabA]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU00740 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU00740 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU00740 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:pabB_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:pabB_context.gif]] | ||
Revision as of 11:56, 13 May 2013
- Description: para-aminobenzoate synthase (subunit A)
| Gene name | pabB |
| Synonyms | pab |
| Essential | no |
| Product | para-aminobenzoate synthase (subunit A) |
| Function | biosynthesis of folate |
| Gene expression levels in SubtiExpress: pabB | |
| Interactions involving this protein in SubtInteract: PabB | |
| Metabolic function and regulation of this protein in SubtiPathways: Phe, Tyr, Trp, Folate | |
| MW, pI | 53 kDa, 5.234 |
| Gene length, protein length | 1410 bp, 470 aa |
| Immediate neighbours | cysK, pabA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00740
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate (according to Swiss-Prot)
- Protein family: anthranilate synthase component I family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P28820
- KEGG entry: [3]
- E.C. number: 2.6.1.85
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Antoine de Saizieu, Pierre Vankan, Cassandra Vockler, Adolphus P G M van Loon
The trp RNA-binding attenuation protein (TRAP) regulates the steady-state levels of transcripts of the Bacillus subtilis folate operon.
Microbiology (Reading): 1997, 143 ( Pt 3);979-989
[PubMed:9084182]
[WorldCat.org]
[DOI]
(P p)
