YmcA

• Description: antagonist of biofilm repression by SinR, control of the phosphorelay
  
  

Gene name	ymcA
Synonyms
Essential	no
Product	antagonist of biofilm repression by SinR
Function	control of biofilm formation and the phosphorelay
Gene expression levels in SubtiExpress: ymcA
Interactions involving this protein in SubtInteract: YmcA
MW, pI	16 kDa, 5.086
Gene length, protein length	429 bp, 143 aa
Immediate neighbours	ymcB, cotE
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, biofilm formation

The gene

Basic information

• Locus tag: BSU17020

Phenotypes of a mutant

• strongly reduced genetic competence, strongly reduced sporulation PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YmcA-YlbF-YaaT, this complex stimulates Spo0A phosphorylation in the phosphorelay PubMed
  • YmcA-Spo0B PubMed
  • YmcA-Spo0F PubMed

• Localization:

Database entries

• Structure: 2PIH

• UniProt: O31779

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ymcA PubMed

• Sigma factor:

• Regulation:
  • expressed during growth and the transition phase, expression is erduced in stationary phase (Spo0A-P) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: