Difference between revisions of "LytH"

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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1047 bp, 349 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1047 bp, 349 aa  
 
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lipA]]'', ''[[yunB]]''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lipA]]'', ''[[fisB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15224&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15224&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=lytH_3321455_3322435_1 lytH] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=lytH_3321455_3322435_1 lytH] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigK]] {{PubMed|12813075}}
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* '''[[Sigma factor]]:''' [[SigK]] {{PubMed|12813075}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  

Revision as of 14:58, 10 February 2013

  • Description: differentiation-associated peptidoglycan hydrolase involved in endospore cortex maturation

Gene name lytH
Synonyms yunA, yutA
Essential no
Product peptidoglycan hydrolase
Function endospore cortex maturation
Gene expression levels in SubtiExpress: lytH
MW, pI 39 kDa, 6.893
Gene length, protein length 1047 bp, 349 aa
Immediate neighbours lipA, fisB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YunA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LytH expression.png















Categories containing this gene/protein

cell wall/ other, sporulation proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

  • Locus tag: BSU32340

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase M23B family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Gavin J Horsburgh, Abdelmadjid Atrih, Simon J Foster
Characterization of LytH, a differentiation-associated peptidoglycan hydrolase of Bacillus subtilis involved in endospore cortex maturation.
J Bacteriol: 2003, 185(13);3813-20
[PubMed:12813075] [WorldCat.org] [DOI] (P p)