CotT

• Description: spore coat protein (inner)
  
  

Gene name	cotT
Synonyms
Essential	no
Product	spore coat protein (inner)
Function	resistance of the spore
Gene expression levels in SubtiExpress: cotT
MW, pI	12 kDa, 9.466
Gene length, protein length	321 bp, 107 aa
Immediate neighbours	ctaO, pdaC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

• Locus tag: BSU12090

Expression

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • inner spore coat PubMed

Database entries

• Structure:

• UniProt: P11863

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: cotT PubMed

• Expression browser: cotT PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:
  • 1S108 ( cotT::cat), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Arthur Aronson, Purdue University, West Lafayette, USA homepage