Difference between revisions of "Mdr"
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| − | + | * '''Description:''' multidrug-efflux transporter (puromycin, nerfloxacin, tosufloxacin) <br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Function''' || drug resistance | |style="background:#ABCDEF;" align="center"|'''Function''' || drug resistance | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 46 kDa, 9.701 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 46 kDa, 9.701 | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:mdr_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:mdr_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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__TOC__ | __TOC__ | ||
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* '''Operon:''' | * '''Operon:''' | ||
| − | * | + | * '''[[Sigma factor]]:''' |
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* '''Regulation:''' expression activated by glucose (3.6 fold) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | * '''Regulation:''' expression activated by glucose (3.6 fold) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | ||
Revision as of 10:56, 7 August 2012
- Description: multidrug-efflux transporter (puromycin, nerfloxacin, tosufloxacin)
| Gene name | mdr |
| Synonyms | ycgD, bmr3 |
| Essential | no |
| Product | multidrug-efflux transporter (puromycin, nerfloxacin, tosufloxacin) |
| Function | drug resistance |
| MW, pI | 46 kDa, 9.701 |
| Gene length, protein length | 1278 bp, 426 aa |
| Immediate neighbours | lctP, ycgE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
transporters/ other, resistance against toxins/ antibiotics
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU03070
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P96712
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation: expression activated by glucose (3.6 fold) PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
