Difference between revisions of "Tmk"
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| − | + | * '''Description:''' thymidylate kinase <br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Function''' || TTP biosynthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || TTP biosynthesis | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]''' | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:tmk_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:tmk_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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* '''Operon:''' | * '''Operon:''' | ||
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=Biological materials = | =Biological materials = | ||
Revision as of 09:26, 7 August 2012
- Description: thymidylate kinase
| Gene name | tmk |
| Synonyms | yaaP |
| Essential | yes PubMed |
| Product | thymidylate kinase |
| Function | TTP biosynthesis |
| Metabolic function and regulation of this protein in SubtiPathways: Nucleotides (regulation) | |
| MW, pI | 23 kDa, 4.866 |
| Gene length, protein length | 636 bp, 212 aa |
| Immediate neighbours | yaaO, yaaQ |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00280
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + dTMP = ADP + dTDP (according to Swiss-Prot)
- Protein family: thymidylate kinase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: P37537
- KEGG entry: [2]
- E.C. number: 2.7.4.9
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
