Difference between revisions of "Mdr"
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|style="background:#ABCDEF;" align="center"|'''Function''' || drug resistance | |style="background:#ABCDEF;" align="center"|'''Function''' || drug resistance | ||
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| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU03070 mdr] | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 46 kDa, 9.701 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 46 kDa, 9.701 | ||
Revision as of 14:52, 6 August 2012
| Gene name | mdr |
| Synonyms | ycgD, bmr3 |
| Essential | no |
| Product | multidrug-efflux transporter (puromycin, nerfloxacin, tosufloxacin) |
| Function | drug resistance |
| Gene expression levels in SubtiExpress: mdr | |
| MW, pI | 46 kDa, 9.701 |
| Gene length, protein length | 1278 bp, 426 aa |
| Immediate neighbours | lctP, ycgE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
transporters/ other, resistance against toxins/ antibiotics
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU03070
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P96712
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation: expression activated by glucose (3.6 fold) PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135]
[WorldCat.org]
[DOI]
(P p)
