Difference between revisions of "CoaX"
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|style="background:#ABCDEF;" align="center"|'''Function''' || coenyzmeA synthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || coenyzmeA synthesis | ||
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| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU00700 coaX] | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/CoA_synthesis.html Coenzyme A]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/CoA_synthesis.html Coenzyme A]''' | ||
Revision as of 14:15, 6 August 2012
| Gene name | coaX |
| Synonyms | yacB |
| Essential | no |
| Product | pantothenate kinase (EC 2.7.1.33) |
| Function | coenyzmeA synthesis |
| Gene expression levels in SubtiExpress: coaX | |
| Metabolic function and regulation of this protein in SubtiPathways: Coenzyme A | |
| MW, pI | 26 kDa, 8.37 |
| Gene length, protein length | 699 bp, 233 aa |
| Immediate neighbours | ftsH, yacC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
biosynthesis of cofactors, cell envelope stress proteins (controlled by SigM, V, W, X, Y)
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00700
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate (according to Swiss-Prot)
- Protein family: type III pantothenate kinase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: P37564
- KEGG entry: [2]
- E.C. number: 2.7.1.33
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Warawan Eiamphungporn, John D Helmann
The Bacillus subtilis sigma(M) regulon and its contribution to cell envelope stress responses.
Mol Microbiol: 2008, 67(4);830-48
[PubMed:18179421]
[WorldCat.org]
[DOI]
(P p)
Leisl A Brand, Erick Strauss
Characterization of a new pantothenate kinase isoform from Helicobacter pylori.
J Biol Chem: 2005, 280(21);20185-8
[PubMed:15795230]
[WorldCat.org]
[DOI]
(P p)
